Jatropha curcas L.: Aspek Botani, Potensi Biofuel, Toksisitas, dan Bioaktivitas
Keywords:
Anticancer, J. curcas, toxicity, biofuelAbstract
This study aims to explain the use (biofuel) and toxicity of J. curcas. This study is based on an online literature study on Google Scholar using the keywords J. Curcas and toxicity of J. curcas. Inedible vegetable oil (biodiesel), such as castor oil, is considered a future raw material because it is a non-edible oil and does not cause food versus fuel conflicts. The potential of J. curcas as a biofuel is related to the oil content consisting of saturated fatty acids, palmitic acid, stearic acid and unsaturated fatty acids, oleic acid, and linoleic acid. Poisoning due to side effects of J. curcas seeds occurs in humans, especially children and also in the environment. Symptoms of poisoning caused by J. curcas can be analyzed through clinical signs, and the effects vary greatly, depending on the concentration, frequency, part eaten and the processing process. Accidentally ingested J. curcas seeds cause clinical syndromes such as restlessness, severe vomiting, and dehydration. Curcacycline A and curcin compound have been successfully identified from J. curcas with antitumor activity. The potential of J. curcas as an antitumor needs to be studied further to find alternative treatments for cancer and tumours.
References
Abobatta, W. (2019). Jatropha curcas: an overview. Journal of Advances in Agriculture, 10, 1650-1656.
Abdelgadir, H.A., & Van Staden, J. (2013). Ethnobotany, ethnopharmacology and toxicity of Jatropha curcas L.(Euphorbiaceae): A review. South African Journal of Botany, 88, 204-218.
Abdu-Aguye, I., Sannusi, A., Alafiya-Tayo, R.A., & Bhusnurmath, S.R. (1986). Acute toxicity studies with Jatropha curcas L. Human toxicology, 5(4), 269-274.
Achten, W.M., Nielsen, L.R., Aerts, R., Lengkeek, A.G., Kjær, E.D., Trabucco, A., ... & Muys, B. (2010). Towards domestication of Jatropha curcas. Biofuels, 1(1), 91-107.
Adam, S.E.I. (1974). Toxic effects of Jatropha curcas in mice. Toxicology, 2(1), 67-76.
Adam, S.E.I., & Magzoub, M. (1975). Toxicity of Jatropha curcas for goats. Toxicology, 4(3), 388-389.
Ahmed, O.M.M., & Adam, S.E.I. (1979). Effects of Jatropha curcas on calves. Veterinary Pathology, 16(4), 476-482.
Augustus, G.D.P.S., Jayabalan, M., & Seiler, G.J. (2002). Evaluation and bioinduction of energy components of Jatropha curcas. Biomass and Bioenergy, 23(3), 161-164.
Azubike, N.C., Okwuosa, C.N., Achukwu, P.U., Maduka, T.C., & Chike, O. (2015). Acute toxicity and histopathological effects of crude aqueous extract of Jatropha curcas leaves in mice. Research Journal of Medicinal Plant, 9(7), 340-346
Azzaz, N.A., El-Nisr, N. A., Elsharkawy, E.E., & Elmotleb, E.A. (2011). Chemical and pathological evaluation of Jatropha curcas seed meal toxicity with or without heat and chemical treatment. Australian Journal of Basic and Applied Sciences, 5(12), 49-59
Babarinde, G.O., Babarinde, S.A., Ojediran, T.K., Odewole, A.F., Odetunde, D.A., & Bamido, T. . (2019). Chemical composition and toxicity of Jatropha curcas seed oil against Sitophilus zeamais Motschulsky as affected by pre-extraction treatment of seeds. Biocatalysis and Agricultural Biotechnology, 21, 101333.
Carels, N. (2009). Jatropha curcas: a review. Advances in Botanical Research, 50, 39-86.
Ciappina, A.L., Ferreira, F.A., Pereira, I.R., Sousa, T.R., Matos, F.S., Reis, P.R.M., ... & Almeida, L.M. (2017). Toxicity of Jatropha curcas L. latex in Allium cepa test. Biosci. J.(Online), 1295-1304.
Chomchai, C., Kriengsunthornkij, W., Sirisamut, T., Nimsomboon, T., Rungrueng, W., & Silpasupagornwong, U. (2011). Toxicity from ingestion of Jatropha curcas ('saboo dum') seeds in Thai children. Southeast Asian Journal of Tropical Medicineand Public Health, 42(4), 946.
Divakara, B.N., Upadhyaya, H.D., Wani, S.P., & Gowda, C.L. (2010a). Biology and genetic improvement of Jatropha curcas L.: a review. Applied Energy, 87(3), 732-742.
Devappa, R.K., Makkar, H.P., & Becker, K. (2010b). Jatropha toxicity - a review. Journal of Toxicology and Environmental Health, Part B, 13(6), 476-507.
Devappa, R.K., Roach, J.S., Makkar, H.P., & Becker, K. (2013). Occular and dermal toxicity of Jatropha curcas phorbol esters. Ecotoxicology and Environmental Safety, 94, 172-178.
Divakara, B.N., Upadhyaya, H.D., Wani, S.P., & Gowda, C.L. (2010). Biology and genetic improvement of Jatropha curcas L.: a review. Applied Energy, 87(3), 732-742.
Ferreira, O.R., Brito, S.S., Lima, F.G., Souza, D.P., Mendonça, S., Ribeiro, J.A.A., ... & Maruo, V.M. (2012). Jatropha curcas pericarp toxicity in sheep. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 64, 559-567.
Gadir, W.A., Onsa, T.O., Ali, W.E.M., El Badwi, S.M.A., & Adam, S.E.I. (2003). Comparative toxicity of Croton macrostachys, Jatropha curcas and Piper abyssinica seeds in Nubian goats. Small Ruminant Research, 48(1), 61-67.
Hallare, A.V., Ruiz, P.L.S., & Cariño, J.E.D. (2014). Assessment of Jatropha curcas L. biodiesel seed cake toxicity using the zebrafish (Danio rerio) embryo toxicity (ZFET) test. Environmental Science and Pollution Research, 21, 6044-6056.
Haas, W., & Mittelbach, M. (2000). Detoxification experiments with the seed oil from Jatropha curcas L. Industrial Crops and Products, 12(2), 111-118.
Powo. (2024). https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:131462-2) diakses 18 September 2024 pukul 10.13.
Jain, S., & Sharma, M.P. (2010). Biodiesel production from Jatropha curcas oil. Renewable and Sustainable Energy Reviews, 14(9), 3140-3147.
Kaushik, N., Kumar, K., Kumar, S., Kaushik, N., & Roy, S. (2007). Genetic variability and divergence studies in seed traits and oil content of Jatropha (Jatropha curcas L.) accessions. Biomass and Bioenergy, 31(7), 497-502.
Koh, M.Y., & Ghazi, T.I.M. (2011). A review of biodiesel production from Jatropha curcas L. oil. Renewable and Sustainable Energy Reviews, 15(5), 2240-2251.
Kywe, T.T., & Oo, M.M. (2009). Production of biodiesel from Jatropha oil (Jatropha curcas) in pilot plant. World Academy of Science, Engineering and Technology, 50, 477-483.
Lasalita-Zapico, F. C., Aguilar, C. H. M., Madas, J. B., & Eroy, M. N. (2012). Chemical composition, antimicrobial properties and toxicity of Jatropha curcas provenances from diverse origins. International Journal of Agriculture and Biology, 14(4), 625-628.
Li, C.Y., Devappa, R.K., Liu, J.X., Lv, J.M., Makkar, H.P.S., & Becker, K. (2010). Toxicity of Jatropha curcas phorbol esters in mice. Food and Chemical Toxicology, 48(2), 620-625.
Liberalino, A.A., Bambirra, E.A., Moraes-Santos, T., & Vieira, E.C. (1988). Jatropha curcas L. seeds: chemical analysis and toxicity. Arquivos de Biologia e Tecnologia, 31(4), 539-550
Lin, J., Yan, F., Tang, L., & Chen, F. (2003). Antitumor effects of curcin from seeds of Jatropha curcas. Acta Pharmacologica Sinica, 24(3), 241-246.
Lu, H., Liu, Y., Zhou, H., Yang, Y., Chen, M., & Liang, B. (2009). Production of biodiesel from Jatropha curcas L. oil. Computers & Chemical Engineering, 33(5), 1091-1096.
Makkar, H.P.S., & Becker, K. (1998). Jatropha curcas toxicity: identification of toxic principle (s). CAB International, Location of publication: Wallingford Country of publication: UK English
Parawira, W. (2010). Biodiesel production from Jatropha curcas: A review. Scientific Research and Essays, 5(14), 1796-1808.
Rakshit, K.D., Darukeshwara, J., Raj, K.R., Narasimhamurthy, K., Saibaba, P., & Bhagya, S. (2008). Toxicity studies of detoxified Jatropha meal (Jatropha curcas) in rats. Food and Chemical Toxicology, 46(12), 3621-3625.
Sawadogo, S., Sanou, S.D., Dabiré, A.P., Belemtougri, G.R., Sawadogo, L., De Leiris, J., ... & Boucher, F. (2018). In vivo evaluation of Jatropha curcas L (Euphorbiaceae) leaves acute and subacute toxicity in mice. Journal of Scientific Research, 10(2), 187-193.
Sharma, S., Dhamija, H. K., & Parashar, B. (2012). Jatropha curcas: a review. Asian Journal of Research in Pharmaceutical Science, 2(3), 107-111.
Silalahi, M., Supriatna, J., & Walujo, E.B. (2015). Local knowledge of medicinal plants in sub-ethnic Batak Simalungun of North Sumatra, Indonesia. Biodiversitas, 16(1), 44-54.
Silitonga, A.S., Atabani, A.E., Mahlia, T.M.I., Masjuki, H.H., Badruddin, I.A., & Mekhilef, S. (2011). A review on prospect of Jatropha curcas for biodiesel in Indonesia. Renewable and Sustainable Energy Reviews, 15(8), 3733-3756.
Sirisha, P., Kumar, A.A., Padmaja, B., & Lakshman, M. (2008). Haematobiochemical changes in Jatropha deoiled seed cake (Jatropha curcas) induced toxicity in broiler chicken and their amelioration. Indian J. Vet. Pathol., 32 (1), 47-51.
Tiwari, A.K., Kumar, A., & Raheman, H. (2007). Biodiesel production from jatropha oil (Jatropha curcas) with high free fatty acids: an optimized process. Biomass and bioenergy, 31(8), 569-575.
Wakandigara, A., Nhamo, L.R.M., & Kugara, J. (2013). Chemistry of phorbol ester toxicity in Jatropha curcas seed - A review. International Journal of Biochemistry Research & Review, 3(3), 146-161.
Wang, X.H., Liu, J.Q., Chen, S., Yin, Y., Liu, Y., & Zhang, C. (2020). Hydroxy-octadecenoic acids instead of phorbol esters are responsible for the Jatropha curcas kernel cake’s toxicity. Communications biology, 3(1), 228.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Marina Silalahi
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
.svg_.png){kind=logo}
